dimer, fibrinogen, and comorbid illness are associated with the course and prognosis of COVID- 19. However, the course of acute severe psychiatric disorders overlapping with COVID-19 infec- tion was not investigated and remained as an unclarified research area. This study aimed to dem- onstrate inflammatory markers and the course of patients suffering from both conditions. Methods: Thirty-eight inpatients with COVID-19 and comorbid acute psychiatric disorders (COVID-19+PD), 31 inpatients with COVID-19, and 38 inpatients with an acute psychiatric disor- der (PD) were included in the study. Neutrophil, lymphocyte counts, serum ferritin, lactate dehydrogenase (LDH), D-dimer, fibrinogen, Systemic immune-inflammation index (SII), neutro- phil/lymphocyte ratio (NLR), and C-reactive protein (CRP) were compared to evaluate inflamma- tion levels. Results: Patients with SARS-CoV-2 infection had older age compared to the PD group. CALL (Comorbidity, age, lymphocyte, lactate dehydrogenase) scores which predict the progression risk in patients with COVID-19 pneumonia, of both COVID-19 groups were found similar. The COVID-19+PD had higher SII in the study sample. Additionally, the COVID-19+PD group had higher NLR, ferritin, and CRP levels than those of the PD group. Conclusions: The prognosis of COVID-19 is not worse when accompanied by a psychiatric disor- der. Laboratory assessment can guide clinicians to distinguish those infected with SARS-CoV-2 within psychiatric inpatient units. The biochemical assessment did not robustly support higher
Eser Adı (dc.title) | Comparison of inflammation markers and severity of illness among patients with COVID-19, acute psychiatric disorders and comorbidity |
Yazar (dc.contributor.author) | Aslı Enez Darçın |
Yayın Yılı (dc.date.issued) | 2022 |
Tür (dc.type) | Makale |
Özet (dc.description.abstract) | dimer, fibrinogen, and comorbid illness are associated with the course and prognosis of COVID- 19. However, the course of acute severe psychiatric disorders overlapping with COVID-19 infec- tion was not investigated and remained as an unclarified research area. This study aimed to dem- onstrate inflammatory markers and the course of patients suffering from both conditions. Methods: Thirty-eight inpatients with COVID-19 and comorbid acute psychiatric disorders (COVID-19+PD), 31 inpatients with COVID-19, and 38 inpatients with an acute psychiatric disor- der (PD) were included in the study. Neutrophil, lymphocyte counts, serum ferritin, lactate dehydrogenase (LDH), D-dimer, fibrinogen, Systemic immune-inflammation index (SII), neutro- phil/lymphocyte ratio (NLR), and C-reactive protein (CRP) were compared to evaluate inflamma- tion levels. Results: Patients with SARS-CoV-2 infection had older age compared to the PD group. CALL (Comorbidity, age, lymphocyte, lactate dehydrogenase) scores which predict the progression risk in patients with COVID-19 pneumonia, of both COVID-19 groups were found similar. The COVID-19+PD had higher SII in the study sample. Additionally, the COVID-19+PD group had higher NLR, ferritin, and CRP levels than those of the PD group. Conclusions: The prognosis of COVID-19 is not worse when accompanied by a psychiatric disor- der. Laboratory assessment can guide clinicians to distinguish those infected with SARS-CoV-2 within psychiatric inpatient units. The biochemical assessment did not robustly support higher |
Açık Erişim Tarihi (dc.date.available) | 2022-01-26 |
Yayıncı (dc.publisher) | European Journal of Psychiatry |
Dil (dc.language.iso) | En |
Konu Başlıkları (dc.subject) | COVID-19 |
Konu Başlıkları (dc.subject) | Psychiatric disorder |
Konu Başlıkları (dc.subject) | Inflammation |
Konu Başlıkları (dc.subject) | Psychotropic |
Tek Biçim Adres (dc.identifier.uri) | https://hdl.handle.net/20.500.14081/1412 |
ISSN (dc.identifier.issn) | 02136163 |
Dergi Sayısı (dc.identifier.issue) | 2 |
Esere Katkı Sağlayan (dc.contributor.other) | Darcin, Asli Enez |
Esere Katkı Sağlayan (dc.contributor.other) | Tuna, Ozgecan |
Esere Katkı Sağlayan (dc.contributor.other) | Dagistan, Ekin |
Esere Katkı Sağlayan (dc.contributor.other) | Ermis, Cagatay |
Esere Katkı Sağlayan (dc.contributor.other) | Salman, Serdar |
DOI (dc.identifier.doi) | 10.1016/j.ejpsy.2022.01.008 |
Orcid (dc.identifier.orcid) | 0000-0001-5831-3040 |
Bitiş Sayfası (dc.identifier.endpage) | 132 |
Başlangıç Sayfası (dc.identifier.startpage) | 125 |
Dergi Cilt (dc.identifier.volume) | 37 |
wosquality (dc.identifier.wosquality) | Q4 |
wosauthorid (dc.contributor.wosauthorid) | DVN-3066-2022 |
Department (dc.contributor.department) | Psikoloji (İngilizce) |
Wos No (dc.identifier.wos) | WOS:000982509700001 |
Veritabanları (dc.source.platform) | Wos |
Veritabanları (dc.source.platform) | Scopus |
Veritabanları (dc.source.platform) | PubMed |