Objective This research was conducted as a prospective, self-controlled, eight-week clinical trial to investigate the effect of kefir consumption on the lipid profile of individuals with normal and dyslipidemic properties. Methods Kefir microorganisms given to volunteer subjects were determined using classical microbial count methods and qReal-Time Polymerase Chain Reaction. The study was carried out with 23 volunteer hospital health personnel between the ages of 20 and 55 who met the research criteria and did not have any health problems. The volunteers regularly consumed kefir on an empty stomach for four weeks. In the last stage, the eight-week study was completed by making blood and anthropometric measurements of the subjects, who continued to be studied without kefir consumption for four more weeks. Results
Considering the changes in the serum lipid profiles of 13 individuals with dyslipidemic symptoms during the 4-week
period they consumed kefir, Total Cholesterol values decreased by 9.15% compared to initial values, LDL-Cholesterol
values decreased by 10.64%, HDL-Cholesterol values decreased by 6.9%, and triglyceride values decreased by 2.46%.
The changes in the serum lipid profiles of 13 individuals with dyslipidemic findings at the end of an eight-week study
were a 5.71% decrease in total cholesterol values (p<0.018) considered statistically significant, as well as a 5.31%
decrease in LDL-Cholesterol values (p<0.021); the HDL-Cholesterol results were found to be significant with an 8.58%
decrease in the values (p<0.035) and insignificant with a 17.21% increase in the triglyceride values (p<0.926). We
concluded that regular kefir consumption was effective in both women and men in lowering total cholesterol and
LDL-Cholesterol from blood lipid profiles, especially in individuals with dyslipidemic symptoms, while this effect was not
observed in normal individuals.
Conclusion
Kefir can positively affect the total cholesterol and LDL-Cholesterol blood parameters of dyslipidemic individuals with
high serum lipid values.
Eser Adı (dc.title) | The effect of kefir consumption on the lipid profile for individuals with normal and dyslipidemic properties: a randomized controlled trial |
Eser Adı (dc.title) | O efeito do consumo de kefir no perfil lipídico em indivíduos com propriedades normais e dislipidêmicas: um ensaio clínico randomizado |
Yazar (dc.contributor.author) | Bahattin Arslan |
Yayın Yılı (dc.date.issued) | 2022 |
Tür (dc.type) | Makale |
Özet (dc.description.abstract) | Objective This research was conducted as a prospective, self-controlled, eight-week clinical trial to investigate the effect of kefir consumption on the lipid profile of individuals with normal and dyslipidemic properties. Methods Kefir microorganisms given to volunteer subjects were determined using classical microbial count methods and qReal-Time Polymerase Chain Reaction. The study was carried out with 23 volunteer hospital health personnel between the ages of 20 and 55 who met the research criteria and did not have any health problems. The volunteers regularly consumed kefir on an empty stomach for four weeks. In the last stage, the eight-week study was completed by making blood and anthropometric measurements of the subjects, who continued to be studied without kefir consumption for four more weeks. Results Considering the changes in the serum lipid profiles of 13 individuals with dyslipidemic symptoms during the 4-week period they consumed kefir, Total Cholesterol values decreased by 9.15% compared to initial values, LDL-Cholesterol values decreased by 10.64%, HDL-Cholesterol values decreased by 6.9%, and triglyceride values decreased by 2.46%. The changes in the serum lipid profiles of 13 individuals with dyslipidemic findings at the end of an eight-week study were a 5.71% decrease in total cholesterol values (p<0.018) considered statistically significant, as well as a 5.31% decrease in LDL-Cholesterol values (p<0.021); the HDL-Cholesterol results were found to be significant with an 8.58% decrease in the values (p<0.035) and insignificant with a 17.21% increase in the triglyceride values (p<0.926). We concluded that regular kefir consumption was effective in both women and men in lowering total cholesterol and LDL-Cholesterol from blood lipid profiles, especially in individuals with dyslipidemic symptoms, while this effect was not observed in normal individuals. Conclusion Kefir can positively affect the total cholesterol and LDL-Cholesterol blood parameters of dyslipidemic individuals with high serum lipid values. |
Açık Erişim Tarihi (dc.date.available) | 2021-12-14 |
Yayıncı (dc.publisher) | Pontificia Universidade Catolica de Campinas |
Dil (dc.language.iso) | En |
Konu Başlıkları (dc.subject) | Cholesterol |
Konu Başlıkları (dc.subject) | Dyslipidemia |
Konu Başlıkları (dc.subject) | Kefir |
Konu Başlıkları (dc.subject) | Probiotics |
Konu Başlıkları (dc.subject) | Triglycerides |
Tek Biçim Adres (dc.identifier.uri) | https://hdl.handle.net/20.500.14081/1661 |
ISSN (dc.identifier.issn) | 1574-017X |
Dergi (dc.relation.journal) | Revista de Nutricao |
Esere Katkı Sağlayan (dc.contributor.other) | Yilmaz, Ilkay |
Esere Katkı Sağlayan (dc.contributor.other) | Arslan, Bahattin |
DOI (dc.identifier.doi) | 10.1590/1678-9865202235e210098 |
Orcid (dc.identifier.orcid) | 0000-0002-6516-4343 |
Dergi Cilt (dc.identifier.volume) | 2022 |
wosquality (dc.identifier.wosquality) | Q4 |
wosauthorid (dc.contributor.wosauthorid) | DNF-7937-2022 |
Department (dc.contributor.department) | Diyetisyen (beslenme ve diyetetik) |
Wos No (dc.identifier.wos) | WOS:000813919500008 |
Veritabanları (dc.source.platform) | Wos |
Veritabanları (dc.source.platform) | Scopus |